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Asthma is
characterized by a hyper-response of the trachea and bronchi
to various stimuli, which results in a narrowing of the airways
in the lung.
Mast cells
are involved in releasing chemical mediators that enhance or
inhibit the asthmatic attack.
Mast cells
have receptors for cAMP and cGMP.
-
c AMP
inhibits the release of histamine.
cAMP is released under
the stimulation of the enzyme adenylate cyclase.
The receptor that activates
this enzyme is the beta-receptor.
Drugs that are beta-receptor
antagonists enhance cAMP release, and inhibit histamine release
that eases the asthmatic attack.
The relative ratios
of cAMP and cGMP have a direct consequence on whether an asthma
attack will occur.
The problem with drugs
is their considerable side effects.
Steroids have unpleasant
side effects including: Inhibiting growth, stomach upset, weight
gain and thinning of bone density.
It is the ability of
C. forskholii
to activate intracellular cAMP that makes it so valuable as a therapeutic
component of AsmaSpray.
Forskolin stimulates the enzyme adenylate cyclase to release cAMP.
cAMP levels rise that inhibits the release of chemical mediators.
This relaxes bronchial smooth muscle and prevents bronchi-spasm.
Coleus Forshkolii
supplementation show benefits where low cAMP is a known factor for various
conditions such as:
Asthma
(Eur. Arch Otor 2001, 258(5), 230-235)
Eczema
(Eur Arch Otor 2001, 258(5), 230-235)
Psoriasis
(Planta Med 1989, Vol.51, 475-476)
Allergies
(J
Cyclic Nucleotide Res 7:201 224,1981)
Low
Thyroid
(Biochim Biophys Acta 2001, 1540(1), 68-81)
Glaucoma
(Opthalmol
Vis Sci 2000, 41(5), 998-1005)
Poor
digestion
( Jpn J physiol 2001,51(4), 435,-444)
Weight
Problems
(Biol Reprod 2001, 65(3), 814-81 9)
Circulation
& Heart
Cardiovasc Res 2001, 51(1), 95-102)
Neurological
Disorders
(J Neurochem 2001, 78(5), 972-980)
Supplement
Facts
Serving Size:
6 sprays = 1ml
Serving Per Container:
180 sprays approx. 30ml
Amount Per Serving Information
Vitamin B3 (Niacin) 5.0mg
Vitamin E 4iu
Gingko Biloba 1.0mg
Coleus Forskohlii 6.25mg
Tylophora Asthmatica 6.25mg
Lutein 1.25mg
Zeaxantin 0.1mg
Other Ingredients:
deionized water, vegetable glycerin, aloe vera, alcohol, trace minerals,
natural flavouring (Anise & Vanilla), grapefruit seed extract, stevia,
potassium sorbate
Other
Ingredients of AsmaSpray: de-ionized water, glycerin, aloe vera, trace
minerals, stevia, natural and artificial flavouring (Anise & Vanilla),
grapefruit seed extract.
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